The Rat Anti-CD49d Antibody from MyBioSource.com is a Rat Monoclonal antibody. This antibody recognizes Mouse antigen. The Rat Anti-CD49d Antibody has been validated for the following applications: Immunohistochemistry.
Description
anti-mouse CD49d monoclonal antibody reacts with a4 integrin, which helps to mediate cell-cell and cell-matrix interactions. a4 integrin combines with b1 and b7 integrin to form VLA-4 and LPAM-1 (Peyers patch homing receptor) respectively. VLA-4 is expressed on most peripheral lymphocytes, thymocytes and monocytes. LPAM-1 is found on peripheral lymphocytes, but few thymocytes. Fibronectin and VCAM-1 act as ligands for both VLA-4 and LPAM-1. LPAM-1 also binds the mucosal vascular addressin MAdCAM-1. (1) Applications of this clone include flow cytometry, immunoprecipitation and immunohistochemistry. (1,2,3)